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About Polyethylene Glycol (PEG) and PEGylation
Amine-Reactive PEG (Linear)
Amine-Reactive PEG (Branched)
Sulfhydryl-Reactive PEG (Linear)
Sulfhydryl-Reactive PEG (Branched)
Carboxy-PEG-Amine Compounds
Methyl-PEG-Amine Compounds

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YOU ARE HERE:  Browse Product Catalog > Crosslinking and Protein Modification > PEGylation Reagents  



PEGylation Reagents 
PEGylate peptides and proteins via available amine or sulfhydryl groups. Increase solubility and stability and reduce immunogenicity of peptides and proteins.

About Polyethylene Glycol (PEG) and PEGylation 
General description of polyethylene glycol (PEG) and a complete listing of PEG-based biotinylation, crosslinker, and modification reagents. 


Amine-Reactive PEG (Linear) 
Methyl-PEG-NHS-ester reagents for PEGylation of proteins and molecules having primary amines. Also called MS(PEG)n, where n = 4, 8, 12 or 24 polyethylene glycol units. 


Amine-Reactive PEG (Branched) 
A branched Methyl-PEG-NHS-ester reagent for PEGylation of proteins and molecules having primary amines. Also called TMS(PEG)12 or (Methyl-PEG12)3-PEG4-NHS Ester. 


Sulfhydryl-Reactive PEG (Linear) 
Methyl-PEG-Maleimide reagents for PEGylation of proteins and molecules having free sulfhydryl groups. Also called MM(PEG)n, where n = 12 or 24 polyethylene glycol units. 


Sulfhydryl-Reactive PEG (Branched) 
A branched Methyl-PEG-Maleimide reagent for PEGylation of proteins and molecules having free sulfhydryl groups. Also called TMM(PEG)12 or (Methyl-PEG12)3-PEG4-Maleimide. 


Carboxy-PEG-Amine Compounds 
PEG amino acids, also called CA(PEG)n, where n = 4, 8, 12 or 24 polyethylene glycol units. The PEGylation compounds can be conjugated to molecules or surfaces using the crosslinker EDC or incorporated into AA sequences during peptide synthesis. 


Methyl-PEG-Amine Compounds 
Also called MA(PEG)n, where n = 4, 8, 12 or 24 polyethylene glycol units. Amino terminus of each PEGylation compound can be conjugated to molecules or surfaces using crosslinkers such as EDC. 

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