SMAD2 and SMAD3 Antibody


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YOU ARE HERE:			Browse Product Catalog > Antibodies > Validated Antibodies for Cellular Proteomics > SMAD2 and SMAD3 Antibody

SMAD2 and SMAD3 Antibody

SMAD3

Gene Description
SMAD family member 3

Alternative Names
MADH3; JV15-2; Smad 3; HSPC193; HsT17436; MGC60396; DKFZP586N0721; DKFZp686J10186

Molecular Weight
50 kDa

Summary
SMAD3 is a critical mediator of the TGF-Beta signaling pathway. It is a sequence specific transcriptional activator, physically binds with AP-1 (Acitvator Protein-1) family members like JunB, JunC and JunD and interacts with response elements to mediate transcriptional activation of target genes. It is also involved in TGF-Beta dependent regulation of steroidogenesis.¹

Western blot data of SMAD3 siRNA transfection experiment.

Western blot data of siRNA transfection experiment. A549 cells were lysed 72 hours after transfection. Cells were transfected with Transfection Reagent alone (Lane 1), 100nM ON-TARGETplus siCONTROL Non-Targeting Pool (Lane 2), or 100nM ONTARGETplus SMAD3 siRNA (Lane 3). Western blot data for GAPDH is included as a control for equal protein loading.

Special Notes
*siRNA targets Human gene product.

References
1. http://www.proteinlounge.com (June 29, 2007).

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Buy	Product #	Description	Pkg. Size	Files	Price
Add	82403	Anti-SMAD2&3 Protein Antibody	120 µl		$279.00

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