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Amine Reactive
Amine Reactive with PEG spacers
Sulfhydryl Reactive
Sulfhydryl Reactive with PEG spacers
Photoreactive

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YOU ARE HERE:  Browse Product Catalog > Crosslinking and Protein Modification > Crosslinking Reagents > Homobifunctional Crosslinkers  



Homobifunctional Crosslinkers 
Crosslinkers with identical reactive groups at either end, enabling one-step conjugation between like functional groups in proteins and other molecules.

Amine Reactive 
These homobifunctional crosslinking reagents feature NHS-ester or imidoester reactive groups and react selectively with primary amines. They are frequently used to stabilize protein-protein interactions for further analysis by immunoprecipitation. 


Amine Reactive with PEG spacers 
Amine-reactive crosslinkers with long, hydrophilic polyethylene glycol (PEG) spacer arms. 


Sulfhydryl Reactive 
Maleimides react with -SH groups at pH 6.5-7.5, forming stable thioether linkages 


Sulfhydryl Reactive with PEG spacers 
Sulfhydryl-reactive crosslinkers with long, hydrophilic polyethylene glycol (PEG) spacer arms. 


Photoreactive 
Reactive when exposed to ultra-violet or visible light 

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