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Thermo Scientific - Pierce Protein Research Products  
Fab Preparation Kits
F(ab')2 Preparation Kits
Mouse IgG1 Fab and F(ab')2 Preparation Kit
IgM Fragmentation Kit

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Antibody Fragmentation Kits 

Optimized reagents and kits based on immobilized papain, pepsin and ficin proteases to selectively cleave IgG and IgM immunoglobulin molecules into Fab, Fab', F(ab')2 and Fc antibody fragments for use in immunodetection and immunoassay procedures.


Digest human or mouse IgG antibodies to make separate Fab and Fc fragments. Kits use immobilized papain and include Protein A spin columns to separate the two types of immunoglobulin fragments. 
 

Digest whole human and other IgG antibodies to make F(ab')2 fragments that retain antigen binding activity. Kits use immobilized pepsin, allowing for efficient digestion without protease contamination.  
 

Efficiently digest mouse IgG1 into Fab or F(ab')2 fragments using Immobilized Ficin. Provides better cleavage and fragment activity for mouse IgG1 than pepsin. Make either Fab or F(ab')2, and purify them from the Fc fragments. 
 

Make better use of whole IgM antibodies by using this kit to create immunoreactive "Fab" or "IgG"-sized antibody fragments. Kit includes immobilized trypsin and pepsin to easily generate a variety of specific IgM fragments. 
 

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