BCL2 Antibody


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Home > Product Catalog > Antibodies > Validated Antibodies for Cellular Proteomics > BCL2 Antibody

BCL2 Antibody

BCL2

Gene Description
B-cell CLL/lymphoma 2

Alternative Names
Bcl-2

Molecular Weight
25-26 kDa

Summary
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants produced by alternate splicing differ in their C-terminal ends.¹

Western blot data of a BCL2 siRNA transfection experiment

Western blot data of a siRNA transfection experiment. HeLa cells were lysed 72 hours after transfection. Cells were transfected with Transfection Reagent alone (Lane 1), 100nM ON-TARGETplus siCONTROL Non-Targeting Pool (Lane 2), or 100nM ON-TARGETplus BCL2 siRNA (Lane 3). Western blot data for GAPDH is included as a control for equal protein loading.

Special Notes
*siRNA targets Human gene product.

References
1. http://www.ncbi.nlm.nih.gov (November 20, 2006).

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Product #	Description	Pkg. Size	Files	Price
82319	Anti-BCL2 Protein Antibody	120 µl		$279.00

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