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Premium Grade Sulfo-NHS-LC-Biotin


Thoroughly tested, highly characterized and fully documented batches of reagent.

Premium Grade Sulfo-NHS-LC-Biotin

Thermo Scientific Pierce Premium Grade Sulfo-NHS-LC-Biotin is our highest quality formulation of this popular amine-reactive biotinylation reagent, specially characterized for applications where product integrity and risk minimization are paramount.

Compared to the standard grade product, Premium Grade Sulfo-NHS-LC-Biotin provides more clearly defined quality and product support by including (a) increased analytical testing and product characterization, (b) greater batch-specific information and quality assurance review, (c) extensive lot sample retention and (d) change control notification. Sulfo-NHS-LC-Biotin is an intermediate-length, water-soluble biotinylation reagent for labeling antibodies, proteins and other molecules that have primary amines. Specific labeling of cell surface proteins is another common application for these uniquely water-soluble and membrane impermeable reagents.

Highlights:

  • Sulfo-NHS-LC-Biotin – popular amine-reactive biotinylation reagent for antibody labeling
  • High quality – identity and purity confirmed by several tests, including quantitative NMR
  • Product integrity – enhanced level of testing and characterization compared to standard grade
  • Lot retention – ample supply of past lots retained to ensure future process testing
  • Change management – Change Control Notification (CCN) service
  • Consistent manufacture – batch-specific manufacturing documentation review

Product Details:

Chemical structure of Sulfo-NHS-LC-Biotin
Chemical structure of Sulfo-NHS-LC-Biotin. This biotinylation reagent labels antibodies and other proteins and molecules that contain primary amines (e.g., side-chain of lysine). For more information, see the product page for standard grade Sulfo-NHS-LC-Biotin or our review of NHS Ester Reaction Chemistry.

 

Specifications of Premium Grade Sulfo-NHS-LC-Biotin. We manufacture biotin reagents to ensure the highest possible overall product integrity, consistency and performance for the intended research applications.
Test Premium Grade Specification Standard Grade
Purity Greater than 90% by quantitative NMR using an internal standard Yes
Visual White to light tan powder, free of foreign material Yes
Solubility Sample dissolves at 10mg/mL in water to give a clear, colorless solution
Sample dissolves at 10mg/mL in DMF to give a clear, colorless solution
Yes
Identity IR scan shows only peaks characteristic of Sulfo-NHS-LC-Biotin Yes
Mass identity Molecular weight of 556 m/z by mass spectrometry
Water content Karl Fischer titration, ≤ 2%
Trace metals All metals, including lead, ≤ 50 ppm
Elemental analysis Reported values for C, H, N, O, and S

Related Resources:

Biotinylation Reagents Selection Guide
Review of Biotinylation Methods and Applications
Chemistry of Crosslinking (and Labeling Reagents)

Related Products:

Premium Grade Reagents – complete menu
Sulfo-NHS-LC-Biotin (standard grade)
All Biotinylation Reagents
Biotin Quantitation Reagents and Kits
Avidin, Streptavidin, NeutrAvidin Affinity Resins


Ordering Information
 
Product # Description Pkg. Size Instructions MSDS CofA Price
PG82075 Premium Grade Sulfo-NHS-LC-Biotin
Formulation: Sulfo-NHS ester of biotin with a 6-aminocaproic acid spacer
Sufficient For: Approx. 50 uses to label a total of 1.2g of IgG using typical conditions
100mg Product Instructions for product #PG82075 Premium Grade Sulfo-NHS-LC-Biotin MSDS for product #PG82075 Premium Grade Sulfo-NHS-LC-Biotin Certificate of Analysis for product #PG82075 Premium Grade Sulfo-NHS-LC-Biotin $294.00

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PG82076 Premium Grade Sulfo-NHS-LC-Biotin
Formulation: Sulfo-NHS ester of biotin with a 6-aminocaproic acid spacer
Sufficient For: Approx. 500 uses to label a total of 12g of IgG using typical conditions
1g Product Instructions for product #PG82076 Premium Grade Sulfo-NHS-LC-Biotin MSDS for product #PG82076 Premium Grade Sulfo-NHS-LC-Biotin Certificate of Analysis for product #PG82076 Premium Grade Sulfo-NHS-LC-Biotin $2,226.00

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Instructions | MSDS | CofA
Product Instructions | MSDS | CofA  

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