Thermo Scientific Pierce Sulfo-MBS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short aromatic spacer arm (7.3 angstroms).
Features of Sulfo-MBS:
• Reactive groups: sulfo-NHS ester and maleimide • Reactive towards: amino and sulfhydryl groups • Non-cleavable • Water-soluble (compare to MBS) • Membrane impermeable, allowing cell surface labeling
Product References: Crosslinker Application Guide -- search for recent literature references for this product