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Single-Use MALDI Matrices


Prepare high-quality MALDI reagents in minutes.

Thermo Scientific single-use MALDI Matrices Sample Pack

Thermo Scientific MALDI Matrices are highly purified, recrystallized reagents packaged in convenient single-use tubes sufficient for analyzing up to 96 samples by matrix assisted laser desorption ionization.

Matrix assisted laser desorption ionization (MALDI) matrices produce the cleanest mass spectrometric (MS) spectra when they are recrystallized and prepared daily, which is inconvenient and typically results in significant waste. The unique packaging of purified, recrystallized alpha-cyano-4-hydroxy-cinnamic acid (CHCA), sinapinic acid (SA) and 2,5-dihydroxybenzoic acid (DHB) MALDI matrices makes it easy to prepare high-quality MALDI reagents in minutes.

Highlights:

  • Single-use packaging saves time and reduces waste
  • Provides accurate quantity of matrix every time

Product Details:

MALDI and electrospray ionization (ESI) are the most common methods to ionize peptides for MS analysis. MALDI is widely used because it is significantly faster than ESI and the ionized molecules are almost exclusively singly charged, making interpretation easier. Also, MALDI is readily automated and highly sensitive. This powerful method for MS peptide analysis is now easier to perform with our single-use, highly pure MALDI matrices that are exceptionally convenient to use.

Chemical structure of cyano-4-hydroxy-cinnamic acid (CHCA) MALDI matrix Chemical structure of dihydroxybenzoic acid (DHB) MALDI matrix Chemical structure of sinapinic acid (SA) MALDI matrix

Chemical structures of MALDI matrices.

References:

  1. Siuzdak, G. (2006). The Expanding Role of Mass Spectrometry in Biotechnology, 2nd Ed., pp 99-107. MCC Press, San Diego, CA.
  2. Zhou, W., et at. (2000). Detection and sequencing of phosphopeptides affinity bound to immobilized metal ion beads by matrix-assisted laser desorption/ionization mass spectrometry. J Am Soc Mass Spectrom 11: 273-82.
  3. Kjellstrom, S. and Jensen, O.N. (2004). Phosphoric acid as a matrix additive for MALDI MS analysis of phosphopeptides and phosphoproteins. Anal Chem 76: 5109-17.

Related Resources:

Mass Spectrometry Sample Prep Workflow - Product Guide
Mass spectrometry technical guide
Quantitative proteomics technical guide
Sample preparation for mass spectrometry technical guide
Tech Tip #50: Process stained polyacrylamide gel pieces for mass spectrometry
MALDI Solutions with LTQ EX and LTQ Orbitrap

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Fe-NTA Phosphopeptide Enrichment Kit
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Ordering Information
 
Product # Description Pkg. Size Instructions MSDS CofA Price
90031 CHCA MALDI Matrix, Single-Use
Formulation: Yellow solid of alpha-cyano-4-hydroxycinnamic acid in transparent green tube
Sufficient For: Analysis of up to 96 samples with each tube after dissolving its contents in 100µL of solvent
24 x 1mg Product Instructions for product #90031 CHCA MALDI Matrix, Single-Use MSDS for product #90031 CHCA MALDI Matrix, Single-Use Certificate of Analysis for product #90031 CHCA MALDI Matrix, Single-Use $150.00

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90032 SA MALDI Matrix, Single-Use
Formulation: Off-white solid of sinapinic acid in transparent purple tube
Sufficient For: Analysis of up to 96 samples with each tube after dissolving its contents in 100μL of solvent
24 x 1mg Product Instructions for product #90032 SA MALDI Matrix, Single-Use MSDS for product #90032 SA MALDI Matrix, Single-Use Certificate of Analysis for product #90032 SA MALDI Matrix, Single-Use $150.00

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90033 DHB MALDI Matrix, Single-Use
Formulation: Off-white solid of 2,5-dihydroxybenzoic acid in transparent blue tube
Sufficient For: Analysis of up to 96 samples with each tube after dissolving its contents in 100μL of solvent
24 x 4mg Product Instructions for product #90033 DHB MALDI Matrix, Single-Use MSDS for product #90033 DHB MALDI Matrix, Single-Use Certificate of Analysis for product #90033 DHB MALDI Matrix, Single-Use $150.00

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90035 MALDI Matrix Sample Pack, Single-Use
Formulation: 8 tubes each of CHCA, SA and DHB reagents
Sufficient For: Analysis of up to 96 samples with each tube after dissolving its contents in 100µL of solvent

Kit Contents:
α-Cyano-4-Hydroxycinnamic Acid (CHCA), 8 x 1mg
Sinapinic Acid (SA), 8 x 1mg
2,5-Dihydroxybenzoic Acid (DHB), 8 x 4mg
3 x 8-tube kit Product Instructions for product #90035 MALDI Matrix Sample Pack, Single-Use MSDS for product #90035 MALDI Matrix Sample Pack, Single-Use Certificate of Analysis for product #90035 MALDI Matrix Sample Pack, Single-Use $150.00

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Instructions | MSDS | CofA
Product Instructions | MSDS | CofA  

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