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Formic Acid


Well-suited for HPLC and mass spectrometry applications.

Pierce Formic Acid

Thermo Scientific Pierce Formic Acid is high-purity solvent supplied in bottles or ampules as a convenient, contamination-free alternative for preparing elution solvents for HPLC separations of protein and peptides.

Pierce Formic Acid is sealed in amber glass ampules under a dry nitrogen atmosphere. A pre-measured aliquot of acid greatly simplifies preparation of liter quantities of mobile phases at the standard 0.1% formic acid concentration. The quality of this formic acid coupled with either glass-ampule bottle packaging provides reliability and convenience that adds value to both the chromatographic and MS results.

Highlights:

  • Greater than 99% pure formic acid – consistent LC baselines, no potential interference introduced in LC or MS applications, and no signal suppression in the mass spectrometer
  • High-performance packaging – choose bottles or amber glass, pre-scored, nitrogen-flushed ampules to protect formic acid from light, moisture and contamination
  • Convenient format – ampule packaging simplifies the preparation of gradient and isocratic mobile phases containing 0.1% (v/v) formic acid in water or acetonitrile; the contents of a single vial in a final volume of 1 L of solvent yields a mobile phase of the most common formic acid concentration.

Product Details:

Chemical structure of formic acid

General properties of formic acid.
Molecular formula HCOOH (CH2O2)
Molecular weight 46.02
Density 1.22g/mL
CAS number 64-18-6
Refractive index 1.3701-1.3721(20ºC)
Flash point 69ºC
Freezing point 8ºC

Pierce Formic Acid is specially purified and tested to the highest specifications to ensure the integrity of your data, maximize sensitivity in your assay and to prolong the life of your equipment.

Specifications of Thermo Scientific Pierce Formic Acid.
Visual Clear liquid, free of particulate matter
Identity (IR) Must show only peaks characteristic for the compound
Purity > 99%
Refractive index 1.3701 to 1.3721 (20°C, 589nm)

Formic acid is a common component of reverse-phase mobile phases that provide protons for LC/MS analysis. The presence of a low concentration of formic acid in the mobile phase is also known to improve the peak shapes of the resulting separation. Unlike trifluoroacetic acid (TFA), formic acid is not an ion-pairing agent and it does not suppress MS ionization of polypeptides when used as a mobile-phase component.

Related Products:

Dimethylsulfoxide (DMSO)
Trifluoroacetic acid (TFA)
Heptafluorobutyric acid (HFBA)
Triethylamine
Acetonitrile
Water


Ordering Information
 
Product # Description Pkg. Size Instructions MSDS CofA Price
28905 Formic Acid, LC-MS Grade
Formulation: Clear, colorless liquid of formic acid (at least 99% pure)
Sufficient For: Liquid chromatography and mass spectrometry applications
10 x 1mL MSDS for product #28905 Formic Acid, LC-MS Grade Certificate of Analysis for product #28905 Formic Acid, LC-MS Grade $76.00

Add to cart
85178 Formic Acid, LC-MS Grade
Formulation: Clear, colorless liquid of formic acid (at least 99% pure)
Sufficient For: Liquid chromatography and mass spectrometry applications
50mL MSDS for product #85178 Formic Acid, LC-MS Grade Certificate of Analysis for product #85178 Formic Acid, LC-MS Grade $118.00

Add to cart

Instructions | MSDS | CofA
Product Instructions | MSDS | CofA  

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