Thermo Scientific™

BMPH (N-β-maleimidopropionic acid hydrazide)

Catalog number: 22297
Thermo Scientific™

BMPH (N-β-maleimidopropionic acid hydrazide)

Catalog number: 22297
Catalog Number
22297
Unit Size
50 mg
Price (USD)
Price: 166.00
Your price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
2229750 mg
Price: 166.00
Your price:
-
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Thermo Scientific Pierce BMPH is a short, maleimide-and-hydrazide crosslinker for conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).

Features of BMPH:

Reactive groups: maleimide and hydrazide
Reactive towards: sulfhydryl groups and carbonyl (aldehyde) groups
• Short (8.1A), sulfhydryl-to-aldehyde crosslinker with simple spacer arm (noncleavable)
• Maleimide group reacts with sulfhydryl groups to form stable thioether linkages
• Hydrazide group conjugates to oxidized sugars of glycoproteins and carbohydrates
• Use sodium meta-periodate to oxidize glycosylation (e.g., sialic acid) to reactive aldehyde groups
• Use with EDC to conjugate primary amine of hydrazide group to carboxyl groups

Product References:

Crosslinker Application Guide -- search for recent literature references for this product

Related Products
EMCH
MPBH
KMUH
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Chemical Reactivity
Carbohydrate-Sulfhydryl
Cleavable
No
Description
BMPH
Molecular Weight (g/mol)
297.19
PEGylated
No
Spacer Arm Length
8.1 Å
Cell Permeability
Yes
Shipping Condition
Ambient
Product Line
Pierce™
Labeling Method
Chemical Labeling
Crosslinker Type
Heterobifunctional
Reactive Moiety
Amine, Hydrazide, Maleimide
Spacer
Short (<10 Å)
Form
Solid
Quantity
50 mg
Solubility
Water
Format
Standard
Water Soluble
Yes
Product Type
Crosslinker

Contents & Storage

Upon receipt store desiccated at 4°C.

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