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A mild reducing agent for cleaving protein disulfide bonds.

Pierce 2-Mercaptoethanol (2-ME)

Thermo Scientific Pierce 2-Mercaptoethanol (2-ME), also called beta-mercaptoethanol (b-ME), is a mild reducing agent for cleaving protein disulfide bonds.


  • Also known as β-mercaptoethanol, beta-mercaptoethanol, bME, b-ME
  • Mild but effective reducing agent, often included in enzyme solutions to protect against catalytic site inactivation due to cysteine sulfhydryl oxidation/disulfide formation; added at final concentrations of 5 and 20mM, with or without EDTA, as an additional protectant

Product Details:

2-Mercaptoethanol; 2-ME

Related Resources:

Overview of crosslinking and protein modification
Overview of protein electrophoresis

Related Products:

All Disulfide Reducing Agents
Ellman’s Reagent – measure sulfhydryls
Electrophoresis Sample Loading Buffers

Ordering Information
Product # Description Pkg. Size Instructions MSDS CofA Price
35602 2-Mercaptoethanol
Formulation: Pure (at least 98% pure; approx. 14.2M) liquid 2-mercaptoethanol
Sufficient For: Preparing 142mL of 100mM solution per 1mL ampule
10 x 1mL MSDS for product #35602 2-Mercaptoethanol Certificate of Analysis for product #35602 2-Mercaptoethanol $55.00

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Instructions | MSDS | CofA
Product Instructions | MSDS | CofA  

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