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New clear milk blocking buffer

Blocking Buffers for Protein Methods

Looking for a more stable, uniform milk-based blocking solution? Try the new Thermo Scientific Pierce Clear Milk Blocking Buffer. This 10X concentrated solution is a long shelf-life, high performance replacement for homemade milk blocking buffers in Western blotting applications.

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The new magnetism of ChIP

Chromatin IP Assay Reagents and Kitsx

If you run ChIP assays (chromatin immunoprecipitation), consider trying the new Thermo Scientific Pierce Magnetic ChIP Kit. It provides a convenient method for efficient isolation of chromatin-bound DNA for subsequent quantitation by PCR.

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Ultra-colorimetric Western blot detection

Western Blotting Substrates

The new 1-Step Ultra TMB-Blotting Solution is an enhanced single-component horseradish peroxidase (HRP) substrate for Western blotting and immunohistochemistry.

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Expanding options for fluorescent labeling

DyLight Fluor Labeling Reagents and Kits

New pegylated DyLight 680 reagents provide expanded versatility for fluorescence imaging applications. The DyLight 680-4xPEG dye contains 4 polyethylene glycol (PEG) chains that are non-cytotoxic, enhance fluorescence and reduce nonspecific binding of conjugates made with them.

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Triple luciferase assays, cell imaging and neuron development

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A new product article, summarizes results on the use of three spectrally-resolvable luciferase reporters and high-content immunofluorescence cellular imaging to monitor phenotypic changes in neuronal precursor cell lines following retinoic acid-induced differentiation.

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Chromatography cartridge LC data

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A new product article on liquid chromatography columns presents results from various experiments that used selected desalting and affinity resins as supplied in the format of Thermo Scientific Pierce Chromatography Cartridges.

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Investigate RNA-Protein interactions

Chromatin IP Assay Reagents and Kitsx

Use the new Pierce Magnetic RNA-Protein Pull-Down Kit to end-label RNA with desthiobiotin and then enrich for target RNA-binding proteins. The complete kit contains sufficient reagents for 20 RNA labeling reactions and 20 protein-RNA pull-down assays.

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Test HA-tagged protein interactions

Co-Immunoprecipitation and Pull-Down Kits

We now offer stand-alone anti-HA magnetic beads and a complete HA-tag magnetic co-IP kit for protein interaction experiments (co-immunoprecipitation) involving HA-tagged fusion proteins.

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A better way to detect S-nitrosylation

Post-Translational Modification Enrichment Kits

Try our new Pierce S-Nitrosylation Western Blot Kit to detect protein S-nitrosocysteine post-translational modifications. This kit improves upon the original biotin-switch method developed by Jeffrey, et al., which used biotin-HPDP to label S-nitrosylated proteins for subsequent Western blot detection via streptavidin-HRP conjugate.

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Scholarship winners and call for new applications

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Congratulations to Douglas Bennion, Brandon Fennell, Jeanette Wat, Jack Huang, Nrithya Sundararaman and David Sanghyuk Han for winning Thermo Scientific Pierce Scholarships for 2012/2013 Winter/Spring!

Learn more about these scientists-in-training and details of the Fall 2013 scholarships totaling $40,000.

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