Video: Dialyze small-volume samples with Slide-A-Lyzer MINI Dialysis Devices


Have you ever wanted to dialyze small-volume samples, but couldn’t risk it with dialysis tubing because of the potential for losing much of your precious sample?

Continue reading…

Protein sample preparation kit for mass spectrometry

Protein Sample Prep Tools for Mass Spectrometry

The new Pierce Mass Spec Sample Prep Kit for Cultured Cells provides the components needed to generate consistent and reproducible protein digests that are directly compatible with LC-MS workflows. The digests do not require further processing, such as C18 clean up or detergent removal.

Continue reading…

Eliminate endotoxins from various protein sources, sizes and charges


Traditional endotoxin removal methods require significant optimization for every target molecule being purified. Furthermore, ionic methods for binding endotoxins require pH optimization to avoid binding highly charged proteins, and size-exclusion methods to filter endotoxins are not effective for large proteins. In this Product Article about removing endotoxins from samples, our scientists demonstrate how they used

Continue reading…

Removing endotoxins from protein samples


Endotoxin removal during the development of biological therapeutics is critical for preventing inflammation, tissue death and endotoxin shock. In this Product Article about removing endotoxins, our scientists discuss how they evaluated a spin-column method that is ideal for protein samples.

Continue reading…

Sample prep methods for mass spectrometry

Protein Mass Spectrometry and HPLC

We have added a page on Sample Preparation for Mass Spectrometry to the Protein Methods Library, which details the various aspects of sample preparation for both MALDI- and ESI-based MS analysis.

Slide-A-Lyzer MINI Dialysis Devices for small samples

Slide-A-Lyzer MINI Dialysis Devices

Thermo Scientific Slide-A-Lyzer MINI Dialysis Devices, 3.5K, 10K and 20K MWCO are disposable polypropylene cups with integrated, low-binding membranes for dialysis and high recovery of proteins and macromolecules in volumes from 10µL to 2mL.

Pierce Detergent Removal Spin Plates

Detergent Removal Resins and Kits

Thermo Scientific Pierce Detergent Removal Resin is now available pre-packed in to 96-well filter spin plates for efficient removal of detergents from multiple samples with minimal sample loss.

New Gamma-irradiated Slide-A-Lyzer G2 Dialysis Cassettes, 10K MWCO

Slide-A-Lyzer G2 Dialysis Cassettes

Thermo Scientific Slide-A-Lyzer G2 Dialysis Cassettes (10K MWCO) provide maximum convenience, flexibility and performance for sample dialysis. These 10K MWCO devices are now available gamma-irradiated.

Pierce TiO2 Phosphopeptide Enrichment and Clean-up Kit

Peptide Sample Prep Tools for Mass Spectrometry

Thermo Scientific Pierce TiO2 Phosphopeptide Enrichment and Clean-up Kit enables fast, selective enrichment of phosphorylated peptides.