Isolate functional synaptosomes while preserving phosphoproteins

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Synaptosomes are commonly used to study synaptic function because they contain functional ion channels, receptors, enzymes and proteins, as well as the intact molecular machinery for the release, uptake and storage of neurotransmitters. Signal transmission is highly regulated by neuronal phosphoproteins, and therefore, maintaining protein phosphorylation during synaptosome preparation is essential.

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Protein glycosylation methods article

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We are proud to present a new article on protein glycosylation and methods to detect and analyze glycoproteins and glycopeptides, respectively. This article is the most recent addition to the series on post-translational modifications in the Protein Methods Library.

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Protect your protein samples from proteases and phosphatases

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Proteases and phosphatases serve many metabolic and regulatory functions; however, upon cell lysis, the once compartmentally contained enzymes are capable of mass protein degradation and dephosphorylation.

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Save money on a highly active endonuclease

Enzymes for Cell Lysis

Our universal nuclease is ideal for cell lysis and a wide variety of other applications. Get the same performance as Benzonase* Nuclease but at a better price.

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Protect your protein samples

Protease Inhibitors and Phosphatase Inhibitors

Thermo Scientific Pierce Protease and Phosphatase Inhibitor Tablets are now available in multiple combinations, including the only combination protease and phosphatase inhibitor tablet, for protecting your protein from degradation and dephosphorylation.

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Obtain neuronal proteins from brain tissue and primary cells

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Neurons have unique morphology and lipid content, making protein extraction from this cell type very challenging. In this Product Article about neuronal protein extraction, our scientists show how the Thermo Scientific N-PER Neuronal Protein Extraction Reagent enables total protein isolation from neuronal tissue or primary cultured cells without adversely affecting protein function.

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