Luciferase detection instrument guide

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Luciferase assays are a powerful way to study gene regulation because of their sensitivity and broad dynamic range. While there are many instruments to use for these and other luciferase-based assays, determining which instrument will work best can be difficult because of their wide feature variability.

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Obtain strong luciferase signals in cells with low transfection efficiency

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Although plasmid-based luciferase assays are powerful tools for studying signal transduction pathways, cells with low transfection efficiency can make signal detection difficult. In this Product Article about performing luciferase assays in Jurkat cells, our scientists demonstrate the effectiveness of using the Thermo Scientific Pierce Luciferase Reporter Systems to transfect Jurkat cells and the Thermo Scientific

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Bioluminescence iPad App

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The American Museum of Natural History* in New York City recently released a free iPad* app as a companion to their Creatures of Light: Nature’s Bioluminescence exhibition.

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Article on bioluminescence and luciferase reporters

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Details on using bioluminescence and luciferase reporters in life science research can now be found in a new article in the Protein Methods Library. Luciferase enzymes are increasing used for in vivo imaging, viability assays and reporter gene assays because of their sensitivity and diversity in substrate requirements and signal duration.

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Brighter solutions for reporter assays

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Thermo Scientific Pierce Luciferase Reporter Vectors, Assays and Reagents deliver greater sensitivity and multiplexing capabilities. Three of these reporters also enable real-time kinetic studies because of their secretory nature.

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Luciferase reporter assays for studying cell signal pathways

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Reporter gene assays are used to study complex cellular signaling pathways. In this Product Article about luciferase assays, our scientists demonstrate how dual-spectral luciferase assay kits can be used to monitor NFkB and CRE promoter activity.

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