Quantitative IP in a high-throughput format

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In a new product article, Dr. Jae Choi and colleagues describe key features of the Pierce qIP Protein Interaction Assay System and then provide example experimental data and demonstrate its use in a high-throughput (HTS) microplate format.

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Forget hash tags! Think c-Myc tag IP.

Immunoprecipitation and Pull-Down Kits

New additions to our lines of magnetic beads and agarose resins provide a complete offering of affinity media to immunoprecipitate, co-immunoprecipitate and pull-down c-Myc-tagged proteins and interactors.

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Quantitative co-IP without elution?

Co-Immunoprecipitation and Pull-Down Kits

The new Pierce qIP Protein Interaction Kits use anti- HA or anti-Myc beads (agarose or magnetic) and a sensitive luciferase assay system to co-immunoprecipitate (co-IP) and quantify interactions between epitope-tagged and Tluc-tagged protein pairs expressed in mammalian cells.

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Powerful ChIP-based analysis

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A new product article describes results of our scientists’ recent study of factors affecting transcriptional regulation by the androgen receptor (AR) and demonstrates one powerful application for the Thermo Scientific Pierce Magnetic ChIP Kit.

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The new magnetism of ChIP

Chromatin IP Assay Reagents and Kitsx

If you run ChIP assays (chromatin immunoprecipitation), consider trying the new Thermo Scientific Pierce Magnetic ChIP Kit. It provides a convenient method for efficient isolation of chromatin-bound DNA for subsequent quantitation by PCR.

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Investigate RNA-Protein interactions

Chromatin IP Assay Reagents and Kitsx

Use the new Pierce Magnetic RNA-Protein Pull-Down Kit to end-label RNA with desthiobiotin and then enrich for target RNA-binding proteins. The complete kit contains sufficient reagents for 20 RNA labeling reactions and 20 protein-RNA pull-down assays.

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Test HA-tagged protein interactions

Co-Immunoprecipitation and Pull-Down Kits

We now offer stand-alone anti-HA magnetic beads and a complete HA-tag magnetic co-IP kit for protein interaction experiments (co-immunoprecipitation) involving HA-tagged fusion proteins.

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Crosslinker Application Guide now available!

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Have you ever looked at our crosslinkers and wondered why you would crosslink your own biomolecules?

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Eliminate IP antibody contamination

Immunoprecipitation Kits (IP Kits)

Easily immobilize an antibody for immunoprecipitation with amine-reactive magnetic beads.

Our new Direct Magnetic IP Kit rapidly delivers clean IPs and fast results, and it can be scaled for high-throughput applications.

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Protein Methods for Protein-Protein Interactions

Protein Interactions

The Protein Methods Library has been updated to include a complete set of articles on considerations and methods for performing protein-protein interaction analysis