Product Article about eliminating endotoxins from various sample types

Eliminate endotoxins from various protein sources, sizes and charges

By Douglas Hayworth

Traditional endotoxin removal methods require significant optimization for every target molecule being purified. Furthermore, ionic methods for binding endotoxins require pH optimization to avoid binding highly charged proteins, and size-exclusion methods to filter endotoxins are not effective for large proteins. In this Product Article about removing endotoxins from samples, our scientists demonstrate how they used the Thermo Scientific Pierce High Capacity Endotoxin Removal Resin to remove endotoxins from a variety of samples while recovering a high percentage of proteins with differing molecular weights and charges.


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Eliminate endotoxins from protein and antibody samples

Eliminate endotoxins from protein and antibody samples