Biomarker breakthroughs using in vitro translation

Biomarker breakthroughs with human expressed protein

By Jared Snider

Biomarkers are antibodies, receptors, peptides, nucleic acids or any other molecule that indicates a biological condition and are increasingly used in the clinic to:

  • diagnose a disease (diagnostic biomarkers)
  • determine the overall survival of patients with a specific disease (prognostic biomarkers)
  • identify patients who will positively or negatively respond to a particular treatment (predictive biomarkers).

While at the Human Proteome Organization (HUPO) Congress in Boston in September, we talked to Dr. Joshua LaBaer, the director of The Biodesign Institute at Arizona State University and a leader in the field of personalized medicine, about how he is using in vitro translation (IVT) and particularly the Thermo Scientific Human IVT system to identify diagnostic biomarkers to screen patients for early stages of various types of cancer.


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