Thermo Fisher Scientific Introduces High-Performance Resin Alternative to Polymixin B Methods for the Removal of Endotoxins
A quick method to remove endotoxins (lipopolysaccharides or LPS) from samples.
FOR IMMEDIATE RELEASE
ROCKFORD, Ill. (Jaunuary 5, 2012) – Thermo Fisher Scientific, the world leader in serving science, today introduced the Thermo Scientific™ Pierce™ High Capacity Endotoxin Removal Resin for the cleanup of protein that is injected or transfected into cells or animals.
The Pierce High Capacity Endotoxin Removal Resin combines porous cellulose beads and an FDA- approved food preservative, poly (ε-lysine), as an affinity ligand to selectively bind endotoxins. Endotoxin levels in protein samples are reduced by greater than 99 percent in as little as one hour using a spin cup format, and protein recovery is greater than 85 percent.
The Pierce High Capacity Endotoxin Removal Resin peptides have a high affinity for the charged glycol-groups of an endotoxin, while the particle pores help trap endotoxins. The modified polylysine affinity ligand eliminates the toxicity concerns associated with alternative technologies that use polymixin B ligands and sodium deoxycholate buffers.
The Pierce High Capacity Endotoxin Removal Resin is available in bulk slurry packages for researchers who want to pack their own columns. This resin can be reused up to five times. The resin is also available in convenient, single-use, spin-column formats, which provide a fast one-hour protocol.
For more information on the new Pierce High Capacity Endotoxin Removal Resin products, please visit www.thermoscientific.com/pierce.
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer. With revenues of nearly $11 billion, we have approximately 37,000 employees and serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as in environmental and process control industries. We create value for our key stakeholders through two premier brands, Thermo Scientific and Fisher Scientific, which offer a unique combination of continuous technology development and the most convenient purchasing options. Our products and services help accelerate the pace of scientific discovery, and solve analytical challenges ranging from complex research to routine testing to field applications. Visit www.thermofisher.com.