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PEPotec Immuno Peptide Libraries


Perform epitope mapping and high-throughout screening with these application-specific peptide libraries.


PEPotec Immuno peptide libraries for epitope mapping and high-throughput screening

Thermo Scientific PEPotec Immuno Peptide Libraries are fully synthetic custom libraries that support high throughput screening assays to map epitopes or identify immunogenic sites in proteins.

PEPotec Immuno peptide libraries are fully customizable and supplied with acetate as the counter ion to avoid potential toxicity issues in epitope discovery and mapping. These application-specific peptide libraries meet the requirements for almost instant use in applications such as vaccine development, T- and B-cell research, antibody development, biomarker discovery and kinase/protease studies. Optional peptide modifications are available, including residue phosphorylation and acetylation, and different formulations are available.

Highlights:

  • Low toxicity – peptides with acetate as the counter ion are less toxic in some experiments than those with trifluoroacetate (TFA) (1)
  • Application-specific – the 6-20-amino acid peptide length distribution fits most immunological applications
  • Convenient – peptides are provided in individual 2-D barcoded tubes in 96-tube plates, and each order includes a CD with the peptide sequences and positions in each plate
  • Flexible – optional services, including phosphorylation and acetylation, are available for studying signaling and regulatory proteins

Applications:

  • Epitope mapping of B- and T-cells
  • Vaccine development
  • Screening of peptide vaccine

Product Details:

PEPotec Immuno Peptide Library Standard Service (Part No. 500100)
Quantity 1-4mg
Length 6 to 20 amino acids; L-isoforms only
Purity Crude (as synthesized)
QC†† Mass spectrometry (MS), 100% of samples
Formulation Lyophilized
Vessel Thermo Scientific Matrix 96-tube plate format (Part No. 3712MTX)
Minimum Order None, but surcharge for orders of <48 peptides
C-terminus Any unmodified L-isoform amino acid
Counter-ion Acetate
Production time ≥8 days (depending on peptide length)
Shipment Room temperature
No purification given, as peptide purity is sequence-dependent and a function of different liquid chromatographic conditions.
†† For all peptides except phosphopeptides, the three major peaks in the MS analysis represent the target of interest. Peptides must pass both the MS analysis and the final gross weight criteria (>1mg) before shipment. If peptides do not pass these criteria, the customer will be informed and one resynthesis will be offered free of charge.

PEPotec Immuno Peptide Library Optional Services
Service Unit Size
Trifluoroacetate (TFA) counter ion Peptide
Phosphorylation at 1 site
Phosphorylation at 2 sites
Lys-Ac, internal
Peptides >20 and <26 amino acids in length
Delivered in 100% DMSO Plate
Alphanumeric tube labeling
Additional modifications upon request.

References:

  1. Pini A. et al. (2011) Efficacy and toxicity of the antimicrobial peptide M33 produced with different counter-ions. Amino Acids, 8 October (epub).

Related Resources:

Peptide Analysis Tool
Antigen Profiler for Robust Peptide Antibody Design

Protein Methods Library: Peptide Synthesis
Protein Methods Library: Peptide Design

Related Products:

Imject KLH-Peptide Conjugation Service
PEPotec SRM Peptide Libraries
Custom Peptide Synthesis Service

Learn about all Peptide Products


Quote Request and Ordering Information
Download the Quote Request/Order Form (1.7mb) Download the peptide order form

Submission Information
For North America:

Email quote requests or orders to
peps@thermofisher.com

OR

Contact your local sales representative or call 1-800-874-3723 or 1-815-968-0747.

For Europe and all other regions:

Email quote requests to services.biopolymers@thermofisher.com

Email orders to sales.peptides@thermo.com

Or contact your local sales representative or Thermo Fisher Scientific in Ulm, Germany at +49-731-29870.

For technical support, please call
1-800-874-3723 or 1-815-968-0747
For technical support, please call +49-731-29870.

Instructions | MSDS | CofA
Product Instructions | MSDS | CofA  

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