Advanced Crosslinking Technologies

Kits and crosslinker systems for specialized crosslinking strategies, including photoreactive amino acids for metabolic labeling, Staudinger reagents for chemoselective ligation, and biotin label transfer compounds for protein interaction experiments.

Selection Guides – Choose a product for your experiment:
- Azide-Phosphine Staudinger Reagent Guide
- In vivo Crosslinking Methods
Protein Methods Library – Learn more about crosslinking techniques:
- Overview of Crosslinking
- Label Transfer Protein Interaction Analysis
Related Product Categories – Other products of interest:


	Controlled Protein-Protein Crosslinking Kit Sulfo-SMCC crosslinker, modification reagents and buffers to chemically conjugate any two purified proteins (antibodies, enzymes, carriers, etc.).


	Sulfo-SBED Biotin Label Transfer Reagent Chemically tag purified proteins at primary amines to covalently crosslink and transfer biotinylation to protein interaction binding partners.


	Sulfhydryl-based Biotin Label Transfer Reagents Chemically tag purified proteins at cysteine sulfhydryls to covalently crosslink and transfer biotinylation to protein interaction binding partners.


	Photoreactive Amino Acids Diazirine analogs of leucine and methionine to express proteins in cell culture that will crosslink their protein interactors upon UV-light activation in vivo.


	NHS-Azide Staudinger Ligation Reagents Activated azido compounds to derivatize proteins or amine surfaces for selective conjugation, detection or purification by phosphine-modified probes.


	NHS-Phosphine Staudinger Ligation Reagents Activated phosphine compounds to derivatize proteins or amine surfaces for selective conjugation, detection or purification of azide-tagged targets.