PEGylation Reagents

Activated linear and branched derivatives of polyethylene glycol (PEG) for pegylation and PEG-modification of peptides and proteins via primary amines and sulfhydryl groups to increase solubility, prolong stability and reduce immunogenicity.

Selection Guides – Choose a product for your experiment:
- About Polyethylene Glycol (PEG) and PEGylation
Protein Methods Library – Learn more about protein modification:
- Overview of Crosslinking and Protein Modification
Related Product Categories – Other products of interest:
- Maleimide Activated PEGylated KLH Carrier Protein
- PEGylated Biotinylation Reagents
- PEGylated Crosslinkers: [amine-to-amine] • [amine-to-sulfhydryl]


	Amine-Reactive PEG (Linear) MS(PEG)n: amine-reactive (NHS ester), methyl-capped polyethylene glycol compounds (4 to 24 EG units) for pegylation of -NH2 groups on proteins (lysines) or assay surfaces.


	Amine-Reactive PEG (Branched) TMS(PEG)n: amine-reactive (NHS ester), 3-branched polyethylene glycol compound (40 EG units) for pegylation of -NH2 groups on proteins (lysines) or assay surfaces.


	Sulfhydryl-Reactive PEG (Linear) MS(PEG)n: sulfhydryl-reactive (maleimide), polyethylene glycol compounds (12 and 24 EG units) for pegylation of protein or peptide cysteines or assay surfaces.


	Sulfhydryl-Reactive PEG (Branched) TMM(PEG)n: sulfhydryl-reactive (maleimide), 3-branched polyethylene glycol compound (40 EG units) for pegylation of protein or peptide cysteines or assay surfaces.


	Carboxy-PEG-Amine Compounds CA(PEG)n: pegylated amino acids of the form carboxy-PEG-amine; with 4 to 24 polyethylene glycol units; for surface- and molecule-pegylation applications.


	Carboxy-PEG-Lipoamide Compounds CL(PEG)n: carboxylic acid and bidentate thiol compound with a 4-unit polyethylene glycol (PEG) spacer; carboxylate and pegylate quantum dots, gold surfaces, silver.


	Carboxy-PEG-Thiol Compounds CT(PEG)n: carboxylic acid and sulfhydryl compound with a 12-unit polyethylene glycol (PEG) spacer; carboxylate and pegylate quantum dots, gold surfaces, silver.


	Methyl-PEG-Amine Compounds MA(PEG)n: methyl- and amine-capped polyethylene glycol compounds containing 4 to 24 PEG units; use for surface-modification and molecule-pegylation applications.


	Methyl-PEG-Lipoamide Compounds ML(PEG)n: methyl and bidentate thiol compound with a 4-unit polyethylene glycol (PEG) spacer; methylate and pegylate quantum dots, gold surfaces, silver.


	Methyl-PEG-Thiol Compounds MT(PEG)n: methyl and sulfhydryl compound with a 4-unit polyethylene glycol (PEG) spacer; methylate and pegylate quantum dots, gold surfaces, silver.