A long-arm, water-soluble, amine-reactive and light-activatable crosslinker based on aryl azide chemistry.
Thermo Scientific Pierce Sulfo-SANPAH is a long-arm (18.2 angstrom) crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester and a photoactivatable nitrophenyl azide.
Optimal photolysis occurs at 320-350 nm; minimizes damage to biomolecules by irradiation
Water soluble; non-cleavable
Reactive groups: nitrophenyl azide and Sulfo-NHS ester
Reactive towards: amino groups
Non-cleavable
Product Details:
Related Products
Sulfo-LC-SDA – efficient photo-reactive diazirine analog of Sulfo-SANPAH
References
Tiberi, M., et al. (1996). J. Biol. Chem. 271(7), 3771-3778.
Wood, C.L. and O’Dorisio, M.S. (1985). Covalent crosslinking of vasoactive intestinal polypeptide to its receptors on intact human lymphoblasts. J. Biol. Chem. 260, 1243-1247. (HSAB example).
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22589
Sulfo-SANPAH
Formulation: Sulfosuccinimidyl 6-(4'-azido-2'-nitrophenylamino)hexanoate; powder solid Sufficient For: 102mL of typical 1X (1mM) reaction solution, or approx. 25 uses at 2mg reagent per use
