Sulfo-KMUS

Thermo Scientific Pierce Sulfo-KMUS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long spacer arm (16.3 angstroms).

Highlights:

• Long aliphatic spacer arm
• Non-cleavable extended aliphatic cross-bridge
• Water-soluble with enhanced sphere of coupling
• Sulfo-NHS ester reacts with primary amines at pH 7-9, forming a stable amide bond
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming a stable thioether bond
• Reactive groups: sulfo-NHS ester and maleimide
• Reactive toward: sulfhydryl and amino groups

Product Details:

References:

1. Fujiwara, K., et al. (1988). Sandwich enzyme immunoassay of tumor-associa- ted antigen sialosylated Lewis (x) using ß-D-galactosidase coupled to a monoclonal antibody of IgM isotype. J. Immunol. Methods. 112, 77-83.

See also: Sulfo-GMBS, Sulfo-EMCS.