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Antibody-Binding Proteins and Conjugates  |
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Protein A binds specifically to the Fc region of immunoglobulins, especially IgG, and is extensively used as a detection molecule for a wide variety of IgG molecules from several species of mammals.
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Recombinant Protein A is a genetically engineered form of Protein A, produced in a non-pathogenic form of Bacillus, that binds with a greater affinity than native Protein A to human IgG3 and rat IgG2a, and does not bind to human IgM, IgD or IgA.
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Protein A/G is a fusion protein combining the IgG binding profiles of Protein A and G. It contains four binding domains from Protein A and two from Protein G, resulting in a high-capacity, high-affinity support that binds to a wide array of antibodies.
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Recombinant Protein binds to the Fc region of many antibodies, but lacks albumin and cell-surface binding sites found in native protein G. Protein G generally has a higher affinity and binds to a broader range of IgG than Protein A.
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Protein L has the unique ability to bind antibodies through kappa light chain interactions without interfering with an antibody's antigen-binding site. This allows Protein L to bind a wider range of Ig classes, as well as to Fab and ScFv fragments.
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Alkaline phosphatase and horseradish peroxidase conjugated to Protein A, G, L and A/G.
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Protein A, Protein G, AP, HRP, BSA, FITC and other molecules tagged with biotin.
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