This 45-page guide is of value to the novice as well as those who have previous experience with crosslinking reagents. It begins with a basic discussion on crosslinking and the reagents that are used. The guide also contains a discussion on various applications where crosslinking has been applied, including the powerful label-transfer technique for identifying or confirming protein interactions. Crosslinking chemistry is dealt with in an easy-to-follow format designed to convey the important information you need without getting lost in details. Each Pierce crosslinking reagent is shown along with it’s structure, molecular weight, spacer arm length and chemical reactivity. The handbook concludes with a list of excellent references on cross-linker use and a glossary of common crosslinking terms.